The key ingredient in magic mushrooms is psilocybin. When psilocybin is taken, it’s converted in the body to psilocin, which is the chemical with the psychoactive properties.1 The Mental Health Facility of the Future Taking mushrooms regularly does not appear to result in physical dependence, and therefore it’s unlikely do magic mushrooms grow in alberta a person will experience difficulty in stopping use.3 There are not many known withdrawal effects, however someone withdrawing from magic mushrooms may experience some psychological effects or fatigue.2 Psilocybin. It can produce muscle relaxation or weakness, ataxia, excessive pupil dilation, nausea, vomiting, and drowsiness. Individuals who abuse psilocybin mushrooms also risk poisoning if one of many existing varieties of poisonous mushrooms is incorrectly identified as a psilocybin mushroom.